Wildtype rat TRPV2 in nanodiscs bound to RR
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 8ffl
Q-score: 0.533
Pumroy RA, De Jesus-Perez JJ, Protopopova AD, Rocereta JA, Fluck EC, Fricke T, Lee BH, Rohacs T, Leffler A, Moiseenkova-Bell V
EMBO Rep (2024) 25 pp. 506-523 [ Pubmed: 38225355 DOI: doi:10.1038/s44319-023-00050-0 ]
Wildtype rat TRPV2 in nanodiscs bound to RR and 2-APB
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8ffm
Q-score: 0.606
Pumroy RA, De Jesus-Perez JJ, Protopopova AD, Rocereta JA, Fluck EC, Fricke T, Lee BH, Rohacs T, Leffler A, Moiseenkova-Bell V
EMBO Rep (2024) 25 pp. 506-523 [ Pubmed: 38225355 DOI: doi:10.1038/s44319-023-00050-0 ]
- Ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2) (559 Da, Ligand)
- Transient receptor potential cation channel subfamily v member 2 (86 kDa, Protein from Rattus norvegicus)
- 2-aminoethyl diphenylborinate (225 Da, Ligand)
- 1,2-didecanoyl-sn-glycero-3-phosphoethanolamine (522 Da, Ligand)
- Tetramer of wildtype rat trpv2 in nanodiscs bound to ruthenium red (340 kDa, Complex from Rattus norvegicus)
RR-bound wildtype rabbit TRPV5 in nanodiscs
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 8ffn
Q-score: 0.577
Pumroy RA, De Jesus-Perez JJ, Protopopova AD, Rocereta JA, Fluck EC, Fricke T, Lee BH, Rohacs T, Leffler A, Moiseenkova-Bell V
EMBO Rep (2024) 25 pp. 506-523 [ Pubmed: 38225355 DOI: doi:10.1038/s44319-023-00050-0 ]
- Ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2) (559 Da, Ligand)
- Ergosterol (396 Da, Ligand)
- Transient receptor potential cation channel subfamily v member 5 (83 kDa, Protein from Oryctolagus cuniculus)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- Tetramer of wildtype rabbit trpv5 in nanodiscs bound to ruthenium red (335 kDa, Complex from Oryctolagus cuniculus)
Wildtype rabbit TRPV5 into nanodiscs in the presence of PI(4,5)P2 and ruthenium red
Resolution: 2.65 Å
EM Method: Single-particle
Fitted PDBs: 8ffq
Q-score: 0.624
Pumroy RA, De Jesus-Perez JJ, Protopopova AD, Rocereta JA, Fluck EC, Fricke T, Lee BH, Rohacs T, Leffler A, Moiseenkova-Bell V
EMBO Rep (2024) 25 pp. 506-523 [ Pubmed: 38225355 DOI: doi:10.1038/s44319-023-00050-0 ]
- 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine (758 Da, Ligand)
- Tetramer of wildtype rabbit trpv5 into nanodiscs in complex with ruthenium red and pi(4,5)p2 (335 kDa, Complex from Oryctolagus cuniculus)
- Ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2) (559 Da, Ligand)
- Ergosterol (396 Da, Ligand)
- Transient receptor potential cation channel subfamily v member 5 (83 kDa, Protein from Oryctolagus cuniculus)
Structure of full-length LexA bound to a RecA filament
Resolution: 2.93 Å
EM Method: Helical reconstruction
Fitted PDBs: 8trg
Q-score: 0.51
Cory MB, Li A, Hurley CM, Carman PJ, Pumroy RA, Hostetler ZM, Venkatesh Y, Gupta K, Petersson EJ, Kohli RM
To Be Published
- Dna (27-mer) (8 kDa, DNA from Escherichia coli)
- Lexa dimer (Complex from Escherichia coli)
- Reca* activated filament (Complex from Escherichia coli)
- Lexa repressor (22 kDa, Protein from Escherichia coli)
- Phosphothiophosphoric acid-adenylate ester (523 Da, Ligand)
- Sos signal complex consisting of reca, ssdna, and lexa (480 kDa, Complex from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- Protein reca (41 kDa, Protein from Escherichia coli)
Inactivated state of 2-APB-bound wildtype rat TRPV2 in nanodiscs
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7n0m
Q-score: 0.49
Pumroy RA, Protopopova AD, Fricke TC, Lange IU, Haug FM, Nguyen PT, Gallo PN, Sousa BB, Bernardes GJL, Yarov-Yarovoy V, Leffler A, Moiseenkova-Bell VY
Nat Commun (2022) 13 pp. 2334-2334 [ DOI: doi:10.1038/s41467-022-30083-3 Pubmed: 35484159 ]
Activated state of 2-APB-bound wildtype rat TRPV2 in nanodiscs
Resolution: 4.15 Å
EM Method: Single-particle
Fitted PDBs: 7n0n
Q-score: 0.372
Pumroy RA, Protopopova AD, Fricke TC, Lange IU, Haug FM, Nguyen PT, Gallo PN, Sousa BB, Bernardes GJL, Yarov-Yarovoy V, Leffler A, Moiseenkova-Bell VY
Nat Commun (2022) 13 pp. 2334-2334 [ DOI: doi:10.1038/s41467-022-30083-3 Pubmed: 35484159 ]
Activated state of 2-APB and CBD-bound wildtype rat TRPV2 in nanodiscs
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7t37
Q-score: 0.483
Pumroy RA, Protopopova AD, Fricke TC, Lange IU, Haug FM, Nguyen PT, Gallo PN, Sousa BB, Bernardes GJL, Yarov-Yarovoy V, Leffler A, Moiseenkova-Bell VY
Nat Commun (2022) 13 pp. 2334-2334 [ DOI: doi:10.1038/s41467-022-30083-3 Pubmed: 35484159 ]
- Cannabidiol (314 Da, Ligand)
- 2-aminoethyl diphenylborinate (225 Da, Ligand)
- Transient receptor potential cation channel subfamily v member 2 (86 kDa, Protein from Rattus norvegicus)
- Tetramer of wildtype rat trpv2 (Complex from Rattus norvegicus)
Inactivated state of 2-APB and CBD-bound wildtype rat TRPV2 in nanodiscs
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7t38
Q-score: 0.46
Pumroy RA, Protopopova AD, Fricke TC, Lange IU, Haug FM, Nguyen PT, Gallo PN, Sousa BB, Bernardes GJL, Yarov-Yarovoy V, Leffler A, Moiseenkova-Bell VY
Nat Commun (2022) 13 pp. 2334-2334 [ DOI: doi:10.1038/s41467-022-30083-3 Pubmed: 35484159 ]
Resolution: 2.27 Å
EM Method: Single-particle
Fitted PDBs: 7rk8
Q-score: 0.717
Martino RA, Murphy J, Wang Q, Hoff H, Pumroy RA, Lee CY, Sims JJ, Roy S, Moiseenkova-Bell VY, Wilson JM
J Virol (2021) 95 pp. e0116421-e0116421 [ Pubmed: 34346767 DOI: doi:10.1128/JVI.01164-21 ]
- Capsid protein vp1 (82 kDa, Protein from Adeno-associated virus 9)
- Adeno-associated virus 9 (Virus from Adeno-associated virus 9)